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Acid Peptic Disease

August 31, 2012  by: Dr. Simran Kaur  Points: 8   Category: Health  Earning $0.17   Views: 586

Acid peptic disease also known as peptic ulcer disease is an ulcer in the lower oesophagus, stomach or duodenum, in the jejunum after surgical anastomosis to stomach and in the ileum adjacent to a Meckel’s diverticulum.

         

Acid peptic disease also known as peptic ulcer disease is an ulcer in the lower oesophagus, stomach or duodenum, in the jejunum after surgical anastomosis to stomach and in the ileum adjacent to a Meckel’s diverticulum.

Causes-

1. Genetic predisposition- family history of gastric ulcers and duodenal ulcers.

2. Digestion of mucosa with acid and pepsin of gastric juice.

3. Very high acid secretion in Zollinger-Ellison Syndrome.

4. Reduced mucosal resistance against acid.

5. Side effects of some medicines.

6. Helicobacter pylori infection.

7. Smoking.

8. Alcohol.


Symptoms-

1. Recurrent abdominal pain localized to epigastrium.

2. Abdominal pain occurs on empty stomach and is relieved by food or antacids and milk.

3. Loss of appetite.

4. Heart burns, vomiting, and excessive salivation.

5. Nausea, dyspepsia.


Investigations-

1. Double contrast barium meal.

2. Endoscopy.

3. Tests for detecting Helicobacter pylori infection.

4. Serum gastrin test.

5. Gastric acid analysis.




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