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Ankylosing Spondylitis

September 05, 2012  by: Dr. Simran Kaur  Points: 8   Category: Health  Earning $0.10   Views: 720

Ankylosing spondylitis is a sero-negative chronic inflammatory arthritis which affects the axial skeleton with a predisposition for lumbar spine and sacroiliac joints.


Ankylosing spondylitis is a sero-negative chronic inflammatory arthritis which affects the axial skeleton with a predisposition for lumbar spine and sacroiliac joints. It usually affects people in second and third decades of life. It affects males more than females.


1. Low back pain with aggravation of pain at night.

2. Low back morning stiffness which improves with exercise or activity and get aggravated by rest.

3. Pain in sacroiliac joints on applying pressure or when the stress on the joint is increased.

4. Chest pain, thoracic kyphosis.

5. Neck pain and a forward stoop of neck.

6. It especially affects lumbar spine, sacroiliac joints, thoracic spine, costovertebral joints, costosternal joints and cervical spine.

7. Peripheral arthritis occurs in advanced stage of disease and is usually asymmetric in nature.

8. Acute anterior uveitis.

9. Iritis.

10. Aortic regurgitation.

11. Myelopathy.

12. Osteoporosis.


1. ESR test.

2. RA factor test.

3. MRI and bone scan.

4. X-ray of affected joints or bone.

5. Serological tests.


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